Journal:

Article Title: Structural and Functional Analysis of Horse Cathelicidin Peptides

doi: 10.1128/AAC.45.3.715-722.2001

Figure Lengend Snippet: Antibacterial activities of eCATH peptides a

Article Snippet: Also important, the 5-40 and 7-40 N-terminally truncated eCATH-3 fragments detected in the tracheobronchial secretions displayed the same activity profile as the full-length peptide (data not shown), thus ruling out the possibility that N-terminal digestion of the peptide is required for improved activity. table ft1 table-wrap mode="anchored" t5 TABLE 2 caption a7 Organism and strain MIC (μg/ml) eCATH-1 eCATH-2 eCATH-3 LLK-eCATH-3 Escherichia coli ATCC 25922 3 14 >150 4.5 Escherichia coli ML35 3 14 >150 4.5 Salmonella enterica serovar Typhimurium ATCC 14028 6 114 >150 9 Salmonella enterica serovar Enteritidis b 6 114 >150 9 Pseudomonas aeruginosa ATCC 27853 12.5 ≥114 >150 18 Serratia marcescens ATCC 8100 12.5 28.5 >150 4.5 Klebsiella pneumoniae ATCC 13883 3 28.5 >150 9 Klebsiella pneumoniae SK1 c 6 114 >150 18 Staphylococcus aureus ATCC 25923 25 57 >150 18 Staphylococcus aureus b (MRSA) 50 114 >150 18 Staphylococcus epidermidis ATCC 12228 6 28.5 >150 18 Streptococcus equinus c 25 >114 >150 9 Bacillus megaterium Bm11 12.5 14 >150 9 Open in a separate window a MICs were determined in Mueller-Hinton broth after incubation at 37°C for 16 to 18 h. Results are the means of three to five independent determinations with a divergence of not more than one MIC. b Horse isolate. c Clinical isolate.

Techniques:

Journal:

Article Title: Structural and Functional Analysis of Horse Cathelicidin Peptides

doi: 10.1128/AAC.45.3.715-722.2001

Figure Lengend Snippet: Antifungal activities of eCATH peptides a

Article Snippet: Also important, the 5-40 and 7-40 N-terminally truncated eCATH-3 fragments detected in the tracheobronchial secretions displayed the same activity profile as the full-length peptide (data not shown), thus ruling out the possibility that N-terminal digestion of the peptide is required for improved activity. table ft1 table-wrap mode="anchored" t5 TABLE 2 caption a7 Organism and strain MIC (μg/ml) eCATH-1 eCATH-2 eCATH-3 LLK-eCATH-3 Escherichia coli ATCC 25922 3 14 >150 4.5 Escherichia coli ML35 3 14 >150 4.5 Salmonella enterica serovar Typhimurium ATCC 14028 6 114 >150 9 Salmonella enterica serovar Enteritidis b 6 114 >150 9 Pseudomonas aeruginosa ATCC 27853 12.5 ≥114 >150 18 Serratia marcescens ATCC 8100 12.5 28.5 >150 4.5 Klebsiella pneumoniae ATCC 13883 3 28.5 >150 9 Klebsiella pneumoniae SK1 c 6 114 >150 18 Staphylococcus aureus ATCC 25923 25 57 >150 18 Staphylococcus aureus b (MRSA) 50 114 >150 18 Staphylococcus epidermidis ATCC 12228 6 28.5 >150 18 Streptococcus equinus c 25 >114 >150 9 Bacillus megaterium Bm11 12.5 14 >150 9 Open in a separate window a MICs were determined in Mueller-Hinton broth after incubation at 37°C for 16 to 18 h. Results are the means of three to five independent determinations with a divergence of not more than one MIC. b Horse isolate. c Clinical isolate.

Techniques: